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Police killed one suspect in the Boston Marathon bombing in a shootout and mounted a house-to-house search for a second man on Friday in Watertown, with much of Boston under virtual lockdown.

Authorities urged everyone to stay at home. Public transportation through the metropolitan area was suspended, and air space restricted. Universities including Harvard and Massachusetts Institute of Technology and public schools were closed.

Officials identified the hunted man as Dzhokhar A. Tsarnaev, 19, and said the dead suspect was his brother, Tamerlan Tsarnaev, 26.

Last night after the FBI released the surveillance pictures showing the two men near the bombing sites as suspects on Thursday, a university police officer was shot and killed on the campus of M.I.T., the Middlesex County District Attorney said in a statement.

A short time later, police received reports of a carjacking by two men who kept their victim inside the car for about half an hour before releasing him, the statement said.

Police pursued that car to Watertown, where explosives were thrown from the vehicle at police and shots were exchanged, the statement said.

The elder brother, Tamerlan, was killed early Friday with a bomb strapped to his chest after the criminal pair "robbed a 7-Eleven, shot a police officer to death, carjacked an SUV and hurled explosives in an extraordinary firefight with law enforcement," according to NBC.

"During the exchange of the gunfire, we believe that one of the suspects was struck and ultimately taken into custody. A second suspect was able to flee from that car and there is an active search going on at this point in time," said Colonel Timothy Alben, superintendent of the Massachusetts State Police.

The wounded suspect was taken to Beth Israel Deaconess Medical Center, where he died with multiple injuries including gunshot wounds and trauma that may have been caused by an explosion, said Dr. Richard Wolfe, chief of emergency medicine, according to Reuters.

The older brother, previously known as Suspect 1, who was seen wearing a dark cap and sunglasses in the FBI images, was pronounced dead.

The FBI on Thursday identified the men as suspects in the twin blasts believed caused by bombs in pressure cookers placed inside backpacks left near the finish line of the Boston Marathon. The blasts killed three people and wounded 176 in the worst attack on U.S. soil since the suicide hijacking attacks of September 11, 2001.